A CLINICAL STUDY OF INTRAOCULAR PRESSURE CHANGES WITH VECURONIUM BROMIDE AND PANCURONIUM BROMIDE

Rocuronium Bromide Versus Vecuronium Bromide

BACKGROUND: Rocuronium Bromide is a newer, low potency nondepolarising neuromuscular blocking agent. It is proven to be five to seven times less potent than vecuronium.The aim of the present study was to evaluate the effectiveness of 2ED95 (2 times effective dose 95) dose (0.6mg/kg) of rocuronium with regard to onset time, the intubating conditions and the duration of action and to compare it w...

Clinical Evaluation of Pipecuronium Bromide and its Comparison with Pancuronium Bromide

The study was carried out to compare the intubating conditions, cardiovascular responses, neuro-muscular blocking properties and reversal characteristics of pipecuronium bromide and pancuronium bromide. This is a prospective hospital based study. 100 patients belonging to ASA grade I or II physical status aged 18 to 70 years were divided into two groups of 50 patients each. Group 1 received pip...

Comparative potency of pipecuronium bromide and pancuronium bromide.

Cumulative dose-response curves were constructed to determine the comparative potency of pipecuronium and pancuronium. From these, the ED50 and ED95 values were calculated. These were 24.96 micrograms kg-1 and 44.96 micrograms kg-1, respectively, for pipecuronium and 30.42 micrograms kg-1 and 61.12 micrograms kg-1, respectively, for pancuronium.

Myocardial stimulation by pancuronium bromide.

The effect of pancuronium bromide on the canine myocardium was studied by observing several indices of myocardial contractility during i.v. and intracoronary infusion of the drug in an anaesthetized, open-chested dog preparation. Pancuronium produced tachycardia when given for 2 min by i.v. and intracoronary infusion with the heart intact. Following denervation and pacing of the heart the intra...

A clinical appraisal of pancuronium bromide and a comparative study of its cardiovascular effect.